Sepsis

Sepsis

Sepsis is a life-threatening condition, with poor and highly variable clinical manifestations, difficult to identify and diagnose. Early diagnosis of sepsis is critical for better disease outcome.

Severe symptoms in sepsis can develop quickly. In effect, the body’s response to combat infection causes organ damage and failure, which in some people leads to death within hours or results in long-lasting effects, if not treated quickly.
Presepsin, a small soluble peptide generated from soluble generated from soluble CD14, is known to function as a regulatory factor that can modules immune response by interacting with T and B Cells. Recent clinical studies indicates that presepsin is a powerful biomarker not only for early diagnoses, but also or risk stratification, and progression prediction in sepsis patients.